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161) What is a method of determining the concentration, activity, or effect of a change to a substance by testing its effect on a living organism and comparing this with the activity of an agreed standard? A) bioassay B) idiosyncrasy C) adverse effect D) potentiation 162) Normally, taken alone, neither substance would cause serious harm, but if taken together, the combination could cause coma or death. This is an example of: A) synergism. B) efficacy. C) duration of action. D) summation. 163) Which of the following is NOT a source of a drug? A) vegetable B) mineral C) animal D) microorganism 164) The chemical analysis of the strength, purity and effectiveness of a drug is termed a(n): A) assay. B) formulary. C) bioassay. D) teratogen. 165) Where in the body are the parasympathetic ganglia located? A) near the target organ B) near the brainstem C) near the spinal cord D) near the sacrum 166) Nicotinic receptors are found on all of the following, EXCEPT: A) cholinergic and adrenergic preganglionic neurons. B) cholinergic and adrenergic postganglionic neurons. C) spinal cord neurons. D) skeletal muscle. 167) This receptor is found on smooth muscles of the pulmonary artery and kidney tubules as well as various sphincters within the GI tract. A) dopamine B) beta2 C) alpha2 D) beta1 168) This is a process in which a cell may decrease the number of receptors exposed to a particular substance to reduce its sensitivity. A) downregulation B) resourcing C) upregulation D) adaptation 169) Which of the following cranial nerves is NOT part of the parasympathetic system? A) six B) three C) seven D) nine 170) Which of the following is NOT a factor that affects drug absorption? A) metabolism rate B) dosage form C) drug solubility D) pH 171) What type of drugs are lipid soluble and readily diffuse across a cell membrane? A) nonionized B) isotonic C) ionized D) hypertonic 172) What is the process of chemically converting drugs into metabolites? A) biotransformation B) excretion C) distribution D) absorption 173) What is the term for the ability of a drug to initiate biological activity as a result of binding to a receptor site? A) efficacy B) affinity C) agonism D) antagonism 174)Â What is the term for the time the body takes to clear one-half of a drug from the body? A) half-life B) therapeutic level C) optimum dose D) duration of action 175)Â Variables to consider when determining the proper method of drug storage include all of the following, EXCEPT: A) potency. B) temperature. C) light.

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